Up-Regulation of the Excitatory Amino Acid Transporters EAAT1 and EAAT2 by Mammalian Target of Rapamycin
Background: The excitatory amino-acid transporters EAAT1 and EAAT2 clear glutamate from the synaptic cleft and thus terminate neuronal excitation.The carriers are subject to regulation by various kinases.The EAAT3 read more isoform is regulated by mammalian target of rapamycin (mTOR).The present study thus explored whether mTOR influences transport